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Table 1 Borrelia burgdorferi B31 candidate OMPs

From: Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes

Protein Outer membrane localization/β-barrel conformationa Signal sequenceb
CELLO PSORTb HHOMP TMBETADISC -ACC PRED-TMBB BOMP SignalP 3.0 PrediSI Signal-CF Kyte Doolittle
Group 1 (6/6)
BB0418 (DipA) + + + + + + + + + +
BB0794 + + + + + + - + + +
BB0795 (BamA) + + + + + + - + + +
BB0838 + + + + + + + + + +
Group 2 (5/6)
BB0110 + + + + + - - - - +
BB0236 + + - + + + - + - +
BB0603 (P66) + + + + + - + + + +
BB0667 + + - + + + - + - +
BB0811 + + - + + + + + + +
BB0824 + - + + + + - + + +
Group 3 (4/6)
BB0027 + - + + + - - - + +
BB0089 + + - + - + + + + +
BB0142 (BesC) + - + + + - - - - +
BB0156 + + - + + - - - + +
BB0159 + + - + + - + - - +
BB0161 + + + - - + - - - +
BB0308 + + - + - + - + + +
BB0319 + + - + - + - - - +
BB0464 + + - + - + + + + +
BB0465 + + + - + - - + + +
BB0543 - + + + + - - + + +
BB0564 - + + + + - - - - +
BB0624 + + - + + - - - - +
BB0662 + + - + + - - + - +
BB0743 + + - + - + - + - +
BB0761 + + - + - + - - - +
Group 4 (3/6)
BB0032 + + - + - - - - + +
BB0039 + - - + - + - + + +
BB0043 + - - + + - - - + +
BB0058 + - - + - + + + + +
BB0102 + + - + - - + + - -
BB0125 + + - + - - - - + -
BB0165 + + - + - - - - - +
BB0322 + + + - + - - - - +
BB0352 + + - + - - + + - +
BB0405 - + + - + - - + + +
BB0406 + + + - - - + + - +
BB0458 + + - + - - - + - +
BB0546 + + - + - - - - + +
BB0735 + + - + - - - + + +
BB0790 + - - + - + - - + +
  1. aProteins are grouped according to the number of OM prediction programs that predict localization to the OM or β-barrel formation. The outer membrane protein prediction programs included CELLO, PSORTb, HHOMP, TMBETADISC-ACC, PRED-TMBB and BOMP
  2. bSignal sequences were predicted by the programs SignalP 3.0, PrediSi, and Signal-CF. Signal sequences were also manually inspected by hydrophilicity plots generated according to the methods of Kyte and Doolittle