TY - JOUR AU - Cigana, Cristina AU - Melotti, Paola AU - Baldan, Rossella AU - Pedretti, Elisa AU - Pintani, Emily AU - Iansa, Patrizia AU - De Fino, Ida AU - Favari, Flavio AU - Bergamini, Gabriella AU - Tridello, Gloria AU - Cirillo, Daniela M. AU - Assael, Baroukh M. AU - Bragonzi, Alessandra PY - 2016 DA - 2016/07/11 TI - Genotypic and phenotypic relatedness of Pseudomonas aeruginosa isolates among the major cystic fibrosis patient cohort in Italy JO - BMC Microbiology SP - 142 VL - 16 IS - 1 AB - Pseudomonas aeruginosa is the predominant pathogen associated with the decline of pulmonary function in cystic fibrosis (CF) patients. Both environment-to-host acquisition and patient-to-patient transmission have been described for P. aeruginosa infection. Epidemic clones and bacterial phenotypic adaptation to the CF lung have been recognised as independent risk factors for disease progression. So far, there is no established link between genotypic prevalence and phenotypic traits. Here, we look at the major CF patient cohort in Italy to identify shared P. aeruginosa clones and associated common phenotypic traits. SN - 1471-2180 UR - https://doi.org/10.1186/s12866-016-0760-1 DO - 10.1186/s12866-016-0760-1 ID - Cigana2016 ER -