Table 2 Summary of sensitivities, specificities, positive and negative predictive values of the boronic acid disk test using different antibiotic substrates with different concentrations of APB, for the phenotypic detection of OXA-48 producers
Antibiotic used in boronic acid disk test | No. of isolates confirmed by PCR as | Test performance | ||||
|---|---|---|---|---|---|---|
Possessing OXA-48 (n = 24) | Not possessing OXA-48 (n = 13) | Sensitivity | Specific | Positive predictive value | Negative predictive value | |
IPM 300 | 17 | 3 | 70.8 % | 76.92 % | 85 % | 58.82 % |
MEM 300 | 18 | 8 | 75 % | 38.46 % | 69.23 % | 45.45 % |
IPM 600 | 19 | 8 | 79.17 % | 38.46 % | 70.37 % | 50 % |
MEM 600 | 20 | 9 | 83.33 % | 30.77 % | 68.97 % | 50 % |