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Table 1 Multiple sequence alignment of vertebrate TFPI-2 C-terminal region showing identical and similar amino acids

From: Vertebrate TFPI-2 C-terminal peptides exert therapeutic applications against Gram-negative infections

Entry & name Latin & name English & name Protein & sequence Net & charge
   MAMMALS   
P48307 Homo sapiens Human CAKALKKKKKMPKLRFASRIRKIRKKQF 14
H2QUX8 Pan troglodytes Chimpanzee CAKALKKKKKMPKLRFASRIRKIRKKQF 14
U3ENJ1 Callithrix jacchus White-tufted-ear marmoset CEKALKKQRKMPKIPFSNRNLKIWKKQF 9
F7CWN2 Macaca mulatta Rhesus macaque CAKALKRKKKIPKFRFASRIRKIRKKQF 14
XP_003896360.1 Papio anubis Olive baboon CAKALKRKKKIPKFRFASRIRKIRKKQF 14
H2PMX0 Pongo abelii Sumatran orangutan CAKALRKKKKMPKLRFASRIRKIRKKQF 14
G3QPC8 Gorilla gorilla gorilla Western lowland gorilla CAKALKRKKKMPKLRFASRIRKIRKKQF 14
XP_008067041.1 Tarsius syrichta Philippine tarsier CVKVLKKKTKVPKLLFANRRRKMQKKQF 12
H0XT57 Otolemur garnettii Small-eared galago CAKALKKEKNKTMPKLPFVNRILKVRK 9
O35536 Mus musculus Mouse CVKGWKKPKRWKIGDFLPRFWKHLS 7
XP_005363735.1 Microtus ochrogaster Prairie Vole CVKAPKKPKKRKTGSGFRIRTKPRRWTP 12
XP_004602345.1 Sorex araneus European shrew CANAMKKYKIKKLQRRHPSRRRSLKIKK 13
EDL84392.1 Rattus Norvegicus Brown Rat CVKALKKPKRRKIGDFLPRFWKLRS 9
XP_010601797.1 Fukomys damarensis Damaraland Mole Rat CEKAYKRGKRKTQKPPFSIKRPKSWRKR 12
H0VU83 Cavia porcellus Guinea pig CEKAYKRGKRKTQIPPFSIRRPKSWKKV 10
XP_007522577.1 Erinaceus europaeus Western European Hedgehog CAKASKKGKIRKMPRGILVNRRETYKKK 11
XP_011361893.1 Pteropus vampyrus Large Flying Fox CIKALKKKQNKKMPKILFVNRNLKMQKK 11
G1PX03 Myotis lucifugus Little brown bat CMKALRKKINKKMPRFFFPDRRRKLQKK 12
XP_006834353.1 Chrysochloris asiatica Cape Golden Mole CTLALKKENNKKMRKSFITNRRLKMRKR 11
XP_008569808.1 Galeopterus variegatus Sunda flying lemur CAKVKKGKNKKILKFPFVVRNLKFRKKK 13
XP_004475751.1 Dasypus novemcinctus Nine-banded Armadillo CENALKKEKKKKIPKGFFAIRRPKIQKK 10
W5NS10 Ovis aries Sheep CVKALKKEKNKKMPRLLFANRRLKIKKQ 11
M3X7K4 Felis silvestris catus Cat CVKALKKEKNKKMPKLFFANRRLKIWKR 11
G3THG9 Loxodonta africana African elephant CTKALKKKKKIQKPLFANRSPQIRK 10
F1SFC1 Sus scrofa Pig CVKALKKEKKMPRLLLASRRLKIKKKQF 11
E2RBF0 Canis familiaris Dog CVKALKKERNKKMTKLSLVNRRLKNWKK 11
G1MHA9 Ailuropoda melanoleuca Giant panda CVKGSRNEKNMQLLKTVFPRRRLKTYKN 8
Q7YRQ8 Bos taurus Bovine CVKALKKEKNKKMPRLLLANRRLKIKKK 12
XP_008684473.1 Ursus maritimus Polar bear CVKGSRKEKNMKLLKTVFPGRRLKTYKK 10
XP_008542988.1 Equus przewalskii Przewalski’s horse CAKGLKKKKNKKMKTLFLANRSLKLQKK 12
XP_007938042.1 Orycteropus afer afer Aardvark CVGFSLKKEKRKKIQKVLFANRRLKIRK 11
XP_007076762.1 Panthera tigris altaica Amur Tiger CVKALKKEKNKKMPKLFFANKRLKIWKR 11
XP_004431409.1 Ceratotherium simum simum Southern White Rhinoceros CTKALKKKKNRKMPKLFLANRSLKLRRK 13
XP_004386213.1 Trichechus manatus latirostris Florida manatee CAKALKKKKKKIRKFVLASRSLKLQKKQ 13
XP_006733001.1 Leptonychotes weddellii Weddell seal CIKAVRKQKDKKTPKIVFAHRRVKTWKK 11
XP_007450700.1 Lipotes vexillifer Yangtze River dolphin CVKALKKGKNKKMPKLLFASRRLKIKKK 13
XP_004265641.1 Orcinus orca Killer Whale CVKALKKGKNKKMPKLLFASRRLKIKKK 13
   BIRDS   
XP_010710984 Meleagris gallopavo Wild Turkey CKKGSQKPTISKPRNLLRRKMMRKLIKK 12
XP_009328855.1 Pygoscelis adeliae Adélie penguin CRKGTQKPRINKPMNVFRRKVMRKLIKK 12
XP_010560815 Haliaeetus leucocephalus Bald eagle CRKAGTQKPRINKPTNVFRRKMMRKLIK 11
XP_005228880.1 Falco peregrinus Peregrine falcon CRKGTQKPRINKPANVFRRKMMRKLTKK 12
XP_009934468.1 Opisthocomus hoazin Hoatzin CRKGTEKPRINKPTNVFRRKMMRKLVKK 11
XP_009893654.1 Charadrius vociferus Killdeer CRKAGAQKPRIDKPTNVFRRKMMRKLIK 10
XP_009639692.1 Egretta garzetta Little egret CRKGTEKPGINKPMNVFRRKMMRKLTKK 10
XP_009672625.1 Struthio camelus australis Ostrich CRKGSEKPRINKPANLLRRKMMRKLIKK 11
XP_009464906.1 Nipponia nippon Crested Ibis CRKGTEKPRINKPTNVFRRKMMRKLIKK 11
XP_009084577.1 Serinus canaria Atlantic canary CRKAGNQKPSINKPTNLSRRKIVRKLKK 11
XP_008919443.1 Manacus vitellinus Golden-collared manakin CRKGTQKPRINKPMSVSRRKIMRKLIKK 12
XP_008492487.1 Calypte anna Anna’s hummingbird CRKAGTQKPKINKPVNGVRRKMMIKLIK 11
XP_005518860.1 Pseudopodoces humilis Ground tit CGKGNQKLRINKPTNVSRRKIVRKLIEK 9
XP_005152979.1 Melopsittacus undulatus Budgerigar CRKGTQKPGINKPMNVFRRKMMRKLVKK 11
XP_005041216.1 Ficedula albicollis The collared flycatcher CRNAGNQKLRINKPTNVSRRKLVRKLIK 10
XP_005010988.1 Anas platyrhynchos Mallard CGKAGSQKPAMKKSTDVFRRKMMRKLIK 9
XP_418662.2 Gallus gallus Chicken CRKGSQKPTINKSRSLLRRKMMRKLIKK 12
XP_005418689.1 Geospiza fortis Medium ground finch CRNGNQKPGINKPTNLSRRKIVRKLKKK 11
XP_005480303.1 Zonotrichia albicollis White-throated Sparrow CRNAGNQKPAINKPANLSRRKIVRKLKK 10
   REPTILES   
XP_005308608.1 Chrysemys picta bellii Western painted turtle CKKAGSKKSSFKKSRNKLPKTMRKLPEK 11
XP_006258519.1 Alligator Mississippiensis American Alligator CRKAGNKKPRIKPKSKVMRKMMRKLQKN 13
   AMPHIBIANS   
Q5FVY6 Xenopus tropicalis Western clawed frog CKKGSKRPRNRNRIRVPRIQS 9
   FISHES   
XP_010889816.1 Esox lucius The northern pike CAKAGKLWKTKNPVTKTAMMKIPKKRSR 10
XP_010739844.1 Larimichthys crocea Croceine croaker CAKGGKKYKRQGKGRRMRRYRNNNITFL 11
XP_008419957.1 Poecilia reticulata Guppy CVRGPKRHSSHGKLRRLRQNRNNHLPLH 8
XP_008329541.1 Cynoglossus semilaevis Cynoglossus CVKGEKKHTGQGMIRRLRRNKNNSIFVV 7
XP_008287494.1 Stegastes partitus Bicolor damselfish CVKGAKKQTGQGKGRRMRRNRHNHITFL 9
XP_007259866.1 Mexican tetra Astyanax mexicanus CARKSKPGKMRRKLIPRKPERRI 10
C3KHI5 Anoplopoma fimbria Sablefish CVTGRKHTIQSKGRRLRRNRINRITFRQ 10
Q1WCN6 Danio rerio Zebrafish CGSKRWSPTKKSVRVSKQYLRRVKPQPS 9
I3JXJ8 Oreochromis niloticus Nile tilapia CAKGWKKHPGRGKILRSRKNRKLVTFLQ 10
XP_003969359.1 Takifugu rubripes Japanese Puffer CVRGRKIRTREGKTNPLRRNRNNRITFM 9
XP_004073873.1 Oryzias latipes Japanese Rice Fish CLKGAKKHTGLKGRDRLMKRNKKTRFMA 10
XP_010772945.1 Notothenia coriiceps Black Rock Cod CARRGKKLTSQVKGRRKRRNRNNRITFL 12
XP_007903512.1 Callorhinchus milii Australian Ghostshark CQKRNKKKTSQKYPTASITRKVVKKNSR 11