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Table 1 In vitro activity of 10 antimicrobial agents against 78 bloodstream infection IRPA isolates

From: Overproduction of active efflux pump and variations of OprD dominate in imipenem-resistant Pseudomonas aeruginosa isolated from patients with bloodstream infections in Taiwan

Antibiotica MIC (μg/mL) % Susceptibility
Range MIC50 MIC90 S I R
Cephems
 Ceftazidime 2–> 128 32 128 29.5 14.1 56.4
 Cefepime 2–> 64 32 64 21.8 16.7 61.5
Monobactam
 Aztreonam 2–> 64 32 64 24.4 21.8 53.8
Carbapenems
 Imipenem 16–256 32 64 0 0 100
 Meropenem 1–64 16 32 2.6 9.0 88.4
 Doripenem 1–128 16 32 3.8 0 96.2
Aminoglycosides
 Amikacin ≤1–> 64 8 32 85.9 5.1 9.0
 Gentamicin ≤1–> 256 8 256 33.3 23.1 43.6
Fluoroquinolones
 Ciprofloxacin ≤0.5–> 64 2 32 47.4 5.1 47.5
 Levofloxacin ≤0.5–> 128 4 64 42.3 9.0 48.7
  1. MIC50/90, minimum inhibitory concentration for 50 % and 90 % of the isolates, respectively; S, susceptible; I, intermediate resistant; R, resistant
  2. aAll isolates were susceptible to colisin, as determined by the disc diffusion method