Fig. 3
From: Pneumococcal colonization and invasive disease studied in a porcine model
Body temperature and white blood cell counts of piglets infected with S. pneumoniae. Body temperature was recorded daily before inoculation and three times a day after inoculation. Mean body temperature of piglets inoculated intravenously (Panel a) or intranasally (Panel b) with S. pneumoniae are depicted. White blood cell counts were determined daily, mean counts are depicted for piglets inoculated intravenously (Panel c) or intranasally (Panel d). Open symbols represent piglets inoculated with a low dose, closed symbols piglets inoculated with a high dose. Each symbol represents 3 − 5 piglets, error bars show standard deviation. *** p < 0.001 (ANOVA)