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Table 5 Regression results of the CCD

From: Enhanced candicidal compound production by a new soil isolate Penicillium verruculosum MKH7 under submerged fermentation

Factor

Coefficient estimate

F-value

Prob > F

Significance

Intercept

211.23

   

Model

 

71.36

<0.0001

Significant

A

−2.25

1.20

0.2911

 

B

−4.3

4.39

0.0536

 

C

2.4

1.34

0.2643

 

D

2.9

2.06

0.1718

 

AB

−2.41

0.92

0.3529

 

AC

1.05

0.18

0.6811

 

AD

0.79

0.098

0.7581

 

BC

−2.17

0.74

0.4024

 

BD

−5.2

4.26

0.0567

 

CD

−5.44

4.69

0.0469

 

A2

−34.2

316.76

<0.0001

 

B2

−37.99

391.87

<0.0001

 

C2

−36.5

360.97

<0.0001

 

D2

−34.74

327.56

<0.0001

 
  1. *Lack of Fit = 4.69, Coefficient of Variation (%) = 10.41, R2 = 0.9852, Adj R-Squared = 0.9714, Pred R-Squared = 0.9210