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Table 3 Comparison of discrepancies and agreement between the CDS, CLSI and Etest method for 100 Neisseria gonorrhoeae isolates

From: Antimicrobial susceptibility testing of Neisseria gonorrhoeae isolates in Pakistan by Etest compared to Calibrated Dichotomous Sensitivity and Clinical Laboratory Standards Institute disc diffusion techniques

Antibiotics

No. of discrepancies

% Agreement

Kappa value

Minor

Major

Very major

Complete

Essential

 

Methods

CDS

CLSI

CDS

CLSI

CDS

CLSI

CDS

CLSI

CDS

CLSI

CLSI

CDS

Ceftriaxone

00

00

00

00

00

00

100

100

100

100

-

-

Spectinomycin

00

00

00

00

00

00

100

100

100

100

-

-

Penicillin G

40

25

00

00

00

00

60

75

100

100

0.5652

0.3435

Ciprofloxacin

10

14

00

00

00

00

90

86

100

100

0.0990

0.6718

Tetracycline

-a

37

-a

01

-a

00

-a

62

-a

99

0.2963

-a

Overall

50

76

00

01

00

00

50

23

100

99

-

-

  1. aNot tested
  2. Minor error: test result showed resistant or susceptible and reference results showed intermediate or test results showed intermediate and reference results showed resistant or susceptible
  3. Major error: test result showed susceptible and reference results showed resistant
  4. Very major error: test result showed resistant and reference results susceptible
  5. Complete percent agreement value was percentage agreement achieved when the test and reference method had identical SIR-category of result
  6. Essential percent agreement value was percentage agreement obtained between the reference and test method when minor discrepancies were disregarded