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1
|
FN1275
|
Acriflavin resistance protein B
|
Q8RE51
|
Resistant to aminoglycosides such as amikacin, gentamycin, kanamycin, neomycin and tobromycin as well as to amphiphilic compounds. Thus, inhibiting AcrB function may lead to pathogen’s susceptibility to these antibiotics.
|
|
2
|
FN1321
|
Acetoacetate metabolism regulatory protein atoC
|
Q8RE11
|
Required for catabolism of short-chain fatty acids. Plays role in flagella synthesis, sodium (but not potassium) sensitivity and chemotaxis.
|
|
3
|
ftsZ
|
Cell division protein FtsZ
|
Q8RDQ7
|
Required for proper localization of division plane during bacterial cytokinesis. Inhibition of its GTP-dependent polymerization activity prevents cells to divide
|
|
4
|
FN0724
|
Flavodoxin
|
Q8RFH4
|
Acts as an electron acceptor of pyruvate-oxidoreductase complex. Flavodoxin inhibitors were reported to act against Helicobacter pylori’s infection that causes gastritis or chronic peptic ulcers
|
|
5
|
FN0756
|
Pseudouridine synthase
|
Q8RFE9
|
Catalyze post-transcriptional modifications of cellular RNAs i.e., site-specific isomerisation of uridine.
|
|
6
|
rsgA
|
Putative ribosome biogenesis GTPase RsgA
|
Q8R685
|
Involved in 30S ribosome subunit biogenesis.
|
|
7
|
FN0809
|
Putative tRNA (cytidine(34)-2’-O)-methyltransferase
|
Q8R673
|
Methylates 2’-O-ribose group of cytidine present at 34thposition of tRNA anticodon loop.
|
|
8
|
sigA
|
RNA polymerase sigma factor SigA
|
Q8RE13
|
Essential for survival of bacteria as it regulates transcription of housekeeping promoters.
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