Carbon monoxide releasing molecule-2 (CORM-2) inhibits growth of multidrug-resistant uropathogenic Escherichia coli in biofilm and following host cell colonization

Table 1 Characteristics of the clinical isolates

Isolate	CTX-M subgroup	CTX-M type	ST131 clone	Antibiotic resistance
ESBL 1	CTX-M -9	CTX-M-24	-	CTX, CAZ, CTB, CIP, GEN, MEL, TMP
ESBL 6	CTX-M -1	CTX-M-15	+	CTX, CAZ, CTB, CIP, TMP
ESBL 7	CTX-M -1	CTX-M-15	+	CTX, CAZ, CIP, MEL, TMP
ESBL 9	CTX-M -9	CTX-M-14	-	CTX, CAZ, CIP, MEL, TMP
UPEC 2^a
UPEC 3^a
UPEC 4^a				TMP
UPEC 5^a				CIP

Antibiotic resistance of ESBL-producing isolates (ESBL) and non-ESBL-producing UPEC isolates (UPEC) isolated from urine of patients with UTI. The CTX-M subgroup, CTX-M type and sequence type (ST) 131 are indicated for the ESBL-producing isolates
Abbreviations: cefotaxime (CTX), ceftazidime (CAZ), ceftibuten (CTB), ciprofloxacin (CIP), gentamicin (GEN), mecillinam (MEL), nitrofurantoin (NIT), trimethoprim (TMP)
^asusceptibility tested for NIT, MEL, TMP, CTX, CIP

ISSN: 1471-2180