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Table 3 Gene Ontology (GO) categories of the Salmonella Typhimurium N-15 transcriptome significantly overrepresented in the co-culture with RBL67 compared to mono-culture

From: Bifidobacterium thermophilum RBL67 impacts on growth and virulence gene expression of Salmonella enterica subsp. enterica serovar Typhimurium

GO category p-value Ngenes in category Description of category
Biological process
 GO:051234 4.77E-28 281 establishment of localization
 GO:006810 4.77E-28 281 transport
 GO:051179 6.29E-25 281 localization
 GO:030254 8.34E-15 42 protein secretion by the type III secretion system
 GO:051704 1.80E-14 47 multi-organism process
 GO:051701 3.20E-12 35 interaction with host
 GO:044419 3.20E-12 35 interspecies interaction between organisms
 GO:044403 3.20E-12 35 symbiosis, encompassing mutualism through parasitism
 GO:008643 8.15E-11 52 carbohydrate transport
 GO:046903 4.51E-10 49 secretion
 GO:032940 4.51E-10 49 secretion by cell
 GO:009306 4.51E-10 49 protein secretion
 GO:052047 5.68E-10 26 interaction with other organism via secreted substance involved in symbiotic interaction
 GO:052049 5.68E-10 26 interaction with host via protein secreted by type III secretion system
 GO:052048 5.68E-10 26 interaction with host via secreted substance involved in symbiotic interaction
 GO:052210 5.68E-10 26 interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction
 GO:044046 5.68E-10 26 interaction with host via substance released outside of symbiont
 GO:051649 4.63E-09 49 establishment of localization in cell
 GO:051641 8.25E-09 49 cellular localization
 GO:009405 9.76E-08 26 pathogenesis
 GO:015031 2.55E-06 49 protein transport
 GO:045184 2.55E-06 49 establishment of protein localization
 GO:033036 2.96E-06 50 macromolecule localization
 GO:008104 3.67E-06 49 protein localization
 GO:009401 8.19E-06 33 phosphoenolpyruvate-dependent sugar phosphotransferase system
 GO:007047 2.10E-04 12 cellular cell wall organization
 GO:045229 2.10E-04 12 external encapsulating structure organization
 GO:071555 7.60E-04 12 cell wall organization
 GO:009242 2.19E-03 7 colanic acid biosynthetic process
 GO:052126 2.19E-03 7 movement in host environment
 GO:052192 2.19E-03 7 movement in environment of other organism involved in symbiotic interaction
 GO:044409 2.19E-03 7 entry into host
 GO:046377 2.19E-03 7 colanic acid metabolic process
 GO:051828 2.19E-03 7 entry into other organism involved in symbiotic interaction
 GO:022610 3.83E-03 17 biological adhesion
 GO:007155 3.83E-03 17 cell adhesion
 GO:030001 6.91E-03 33 metal ion transport
 GO:006814 8.26E-03 16 sodium ion transport
 GO:009235 1.23E-02 14 cobalamin metabolic process
 GO:009236 1.23E-02 14 cobalamin biosynthetic process
 GO:015891 2.34E-02 5 siderophore transport
 GO:019184 2.34E-02 5 nonribosomal peptide biosynthetic process
 GO:006811 2.34E-02 47 ion transport
 GO:015672 2.61E-02 27 monovalent inorganic cation transport
 GO:006812 3.45E-02 37 cation transport
 GO:006778 4.86E-02 16 porphyrin metabolic process
 GO:006779 4.86E-02 16 porphyrin biosynthetic process
Molecular function
 GO:005215 4.79E-20 215 transporter activity
 GO:015144 1.57E-09 39 carbohydrate transmembrane transporter activity
 GO:022892 1.31E-08 111 substrate-specific transporter activity
 GO:022891 9.42E-08 99 substrate-specific transmembrane transporter activity
 GO:051119 9.81E-08 34 sugar transmembrane transporter activity
 GO:022857 1.61E-07 107 transmembrane transporter activity
 GO:008324 1.82E-07 64 cation transmembrane transporter activity
 GO:005402 1.79E-06 29 cation:sugar symporter activity
 GO:015075 5.82E-06 70 ion transmembrane transporter activity
 GO:015291 6.89E-06 44 secondary active transmembrane transporter activity
 GO:015294 6.89E-06 34 solute:cation symporter activity
 GO:015293 6.89E-06 34 symporter activity
 GO:015295 6.89E-06 27 solute:hydrogen symporter activity
 GO:005351 6.89E-06 27 sugar:hydrogen symporter activity
 GO:022804 5.84E-05 71 active transmembrane transporter activity
 GO:015082 6.07E-03 13 di-, tri-valent inorganic cation transmembrane transporter activity
 GO:046873 7.20E-03 23 metal ion transmembrane transporter activity
 GO:022890 9.53E-03 28 inorganic cation transmembrane transporter activity
 GO:015149 1.06E-02 8 hexose transmembrane transporter activity
 GO:015145 1.06E-02 8 monosaccharide transmembrane transporter activity
 GO:015343 2.20E-02 5 siderophore-iron transmembrane transporter activity
 GO:042927 2.20E-02 5 siderophore transporter activity
 GO:005381 2.59E-02 8 iron ion transmembrane transporter activity
 GO:046915 2.59E-02 11 transition metal ion transmembrane transporter activity
 GO:042879 2.59E-02 6 aldonate transmembrane transporter activity
 GO:015128 2.59E-02 6 gluconate transmembrane transporter activity
 GO:005506 3.93E-02 16 iron ion binding
 GO:046943 4.82E-02 26 carboxylic acid transmembrane transporter activity
 GO:005342 4.82E-02 26 organic acid transmembrane transporter activity
Cellular component
 GO:016020 6.15E-12 381 membrane
 GO:030257 3.05E-10 26 type III protein secretion system complex
 GO:005886 2.84E-08 314 plasma membrane
 GO:044425 5.28E-06 129 membrane part
 GO:016021 5.28E-06 124 integral to membrane
 GO:031224 5.28E-06 124 intrinsic to membrane
 GO:009279 4.20E-05 47 cell outer membrane
 GO:019867 3.67E-04 47 outer membrane
 GO:043234 4.76E-04 50 protein complex
 GO:009289 9.12E-04 15 pilus
 GO:044462 2.45E-03 104 external encapsulating structure part
 GO:043190 3.32E-02 4 ATP-binding cassette (ABC) transporter complex