Genotypic and phenotypic analysis of clinical isolates of Staphylococcus aureus revealed production patterns and hemolytic potentials unlinked to gene profiles and source

Table 3 Characterisation of clonal complexes and comparison of alpha toxin production rates

Clonal complex	ST (n)	spa (n)	agr (n)	Superantigens^b	Production (m/sd)^d α toxin
CC5	ST5 (3)	t071, t548, t002	II (3)	selp (2), egc (3), selw (3), selx (3)	1.1 (+/−0.7)
CC5	ST1457 (1)	t067	II	tst, selp, egc, selw, selx	1.1 (+/−0.7)
CC6	ST6 (1)	t3802	I	sea, selx
ST7	ST7 (3)	t091 (3)	I (3)	selp (3), selx (3)	1.32 (+/−0.55)
CC8	ST8 (4)	t3308, t024, t008, t648	I (5)	sea (1), selx (4)	8.78 (+/−10.23)
	ST3275 (1)^a	t008	I (5)	sea (1), selx (1)
	ST630 (1)	t377	IV	selx
CC10	ST10 (1)	t6873	II	seb, seh, egc, selx
CC15	ST15 (2)	t2453, t084	II (5)	selx (2)	0.42 (+/−0.55)
CC15	ST582 (3)	t084 (3)	II (5)	selx (3)	0.42 (+/−0.55)
CC22	ST22 (3)	t790, t13078, t005	I (3)	sec (1), sell (1), egc (3), selx (3)	15.93 (+/−18.43)
CC25	ST25 (1)	t3232	I	egc, selx
CC30	ST30 (10)	t433 (2), t4401, t11980, t617, t012, t021 (2), t342 (2)	III (10)	tst (5), sea (5), egc (10), selx (10)	≤0.01
CC30	ST34 (2)	t3805, t15407	III (2)	tst (2), seh (2), egc (2), selx (2)	≤0.01
CC45	ST45 (8)	t015 (2), t333, t230, t583, t065, t350, t553	I (8)	sec (5), sell (5), egc (8), selx (8)^c	4.69 (+/−2.36)
CC50	ST50 (2)	t246 (2)	IV (2)	egc (2), selx (2)
CC51	ST121 (2)	t284, t1441	IV (2)	egc (2), selx (2)
CC101	ST101 (2)	t056 (2)	I (2)	selx (2)
CC779	ST779 (1)	t878	III	sed, sej, selr, selx

^aStrain 767 N-10 displayed a different allele of aroE, being a new single locus variant of ST8
^bAll superantigen genes were included with the exception of pseudogenes
^cSuperantigen-like gene selx including frameshift nonsense mutation (I11)
^dMean (m) and standard deviation (sd) of production rates were determined of CC groups comprising one or more STs (number of strains n ≥ 3)

ISSN: 1471-2180