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Table 4 Recombination frequencies determined for H. pylori strains

From: Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function

Strain genotype na Recombinant frequency (x10−4) Relative value P value (MWU)
Wt 30 4.96 (±3.78) 1  
Wt + hpmutS2 14 0.963 (±0.97) 0.19 <0.0001
Wt + hpmutS2-G338R 15 4.18 (±4.87) 0.84 0.802
Wt + hpmutS2-E413A 18 23.4 (±17.8) 4.71 <0.0001
hpmutS2 36 39.2 (±29.2) 7.9 <0.0001
hpmutS2  + hpmutS2 27 1.00 (±4.29) 0.20 0.0003
hpmutS2  + hpmutS2-G338R 30 25.2 (±22.9) 5.08 <0.0001
hpmutS2  + hpmutS2-E413A 21 45.2 (±54.4) 9.11 <0.0001
  1. The recombination frequencies were calculated as the number of streptomycin resistance colonies per recipient cfu. Values correspond to the average and standard deviation. P values were calculated using the Mann–Whitney U test. na No. of independent determinants