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Fig. 4 | BMC Microbiology

Fig. 4

From: Lactobacillus crispatus inhibits growth of Gardnerella vaginalis and Neisseria gonorrhoeae on a porcine vaginal mucosa model

Fig. 4

Unbuffered RPMI does not support sufficient pH changes in the presence of L. crispatus on PVM. Unbuffered RPMI was placed under transwells and relevant explants were inoculated with L. crispatus. After 48 h, relevant explants were inoculated with G. vaginalis. Experiments were performed under anaerobic conditions and the pH of media below explants was monitored over time. a Media under uncolonized controls (CNTL) and those colonized with G. vaginalis (GV) alone reached pH 6.5 while those colonized with L. crispatus (LC) alone or co-colonized with both organisms (LC + GV) reached pH 6.0 (N = 4, n = 1). b The presence of L. crispatus had a statistically significant (asterisk, p < 0.016), yet minor effect on G. vaginalis growth. Dotted line represents GV inoculum

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