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Fig. 3 | BMC Microbiology

Fig. 3

From: Lactobacillus crispatus inhibits growth of Gardnerella vaginalis and Neisseria gonorrhoeae on a porcine vaginal mucosa model

Fig. 3

Various acids inhibit growth of G. vaginalis and N. gonorrhoeae on PVM. RPMI was pH-adjusted with lactic acid, acetic acid or hydrochloric acid (HCl) and placed under transwells containing PVM explants. Bacteria were enumerated 48 h post-colonization. L. crispatus and G. vaginalis were incubated anaerobically, while N. gonorrhoeae was incubated aerobically. a The low pH produced by each of the three acids has no effect on growth of L. crispatus. b G. vaginalis growth is inhibited at pH 4.0 in the presence of all three acids. c N. gonorrhoeae growth peaked at pH 5.5 in the presence of lactic acid and HCl, while growth was inhibited at pH 5.5 in the presence of acetic acid. Asterisks indicate significant difference from inoculum (dotted lines) (p < 0.0001)

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BMC Microbiology

ISSN: 1471-2180

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