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Table 1 Antisense PNAs used in this study

From: Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro

PNA 5′ − > 3′ sequence Target gene (target region around ATG)
A55 KFFKFFKFFK-eg1-ttcatcaata-CONH2 mecA (−5 to +5)
A73 KFFKFFKFFK-O-catcaatatc-CONH2 mecA (−7 to +3)
A82 KFFKFFKFFK-eg1-atcaatatcc-CONH2 mecA (−8 to +2)
A101 KFFKFFKFFK-O-caatatcctc-CONH2 mecA (−10 to −1)
scrA KFFKFFKFFK-O-cactataatc-CONH2 N.A.
A73-EJH MINWKLRLKNK-O-catcaatatc-CONH2 mecA (−7 to +3)
scrA-EJH MINWKLRLKNK-O-cactataatc-CONH2 N.A.
A73-Tat YGRKKRRQRRR-O-catcaatatc-CONH2 mecA (−7 to +3)
scrA-Tat YGRKKRRQRRR-O-cactataatc-CONH2 N.A.
Z19 KFFKFFKFFK-eg1-TTCTAACATT-NH2 ftsZ (−1 to +9)
Z46 KFFKFFKFFK-eg1-TAACATTTAA-NH2 ftsZ (−4 to +6)
scrZ KFFKFFKFFK-eg1-AATTACTATA-NH2 N.A.