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Fig. 5 | BMC Microbiology

Fig. 5

From: Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro

Fig. 5

Reduction of ftsZ mRNA in MRSA and MRSP by anti-ftsZ PNA. Bacterial cultures were treated with indicated concentrations of anti-ftsZ PNA, Z46, and scrambled PNA, scrZ in the absence of oxacillin and grown to early log phase. RNA was extracted and ftsZ expression was quantified by qPCR, normalized to pta and gyrA for (a) NCTC 13142, and proC and pyk for (b) HH-1. Normalized mRNA values were calculated relative to the untreated control in each experiment, and plotted as mean ± SD of n = 3. *p < 0.05, **p < 0.01

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