Molecular epidemiology of carbapenem resistant Enterobacteriaceae in Valle d’Aosta region, Italy, shows the emergence of KPC-2 producing Klebsiella pneumoniae clonal complex 101 (ST101 and ST1789)

Table 1 Antibiotic susceptibility profiles of carbapenem resistant K. pneumoniae and E. coli

MIC^a (mg/l)
Antibiotic	K. pneumoniae (51 total stains)			E. coli (6 total strains)
	MIC₅₀	MIC₉₀	Range	MIC₅₀	MIC₉₀	Range
Amoxicillin	≥32	≥32	16 - ≥ 32	≥32	≥32	≥32
Piperacillin-Tazobactam	≥128	≥128	≥128	≥128	≥128	≥128
Ceftazidime	≥64	≥64	>4 - ≥ 64	≥64	≥64	≥64
Cefotaxime	≥64	≥64	8 - ≥ 64	≥64	≥64	≥64
Cefepime	≥64	≥64	>4 - ≥ 64	≥64	≥64	≥64
Imipenem	>16	>16	>8 - ≥ 16	≥16	≥16	≥16
Meropenem	≥16	≥16	≥16	≥16	≥16	>8 - ≥ 16
Ertapenem	≥8	≥8	4 - ≥ 8	>1	2	>1 - 2
Fosfomycin	64	≥256	≤16 - ≥ 256	≤16	≤16	≤16
Amikacin	32	≥64	≤2 - ≥ 64	≤2	≤2	≤2
Gentamicin	8	≥16	≤1 - ≥ 16	2	2	≤1- 2
Ciprofloxacin	≥4	≥4	>1 - ≥ 4	≥4	≥4	≥4
Trimethoprim-Sulfamethoxazole	≤20	≥320	≤20 - ≥ 320	≥320	≥320	≤20 - ≥ 320
Colistin	≤0,5	≤0,5	≤0,5 - 125	≤0,5	≤0,5	≤0,5

ISSN: 1471-2180