Fig. 2
LIPS detection of antibody levels to the eight most informative MTB proteins. Antibodies against eight antigens including PstS1, FbpA, Rv0831C, EspB, Ssb, HspX, BfrB and Mpt64, were measured by LIPS. Each symbol represents individual samples from cohort 2 including 53 with pulmonary TB, 7 with disseminated TB and 22 controls. Each symbol represents individual subjects with antibody levels in light units (LU) plotted on the Y-axis using a log10 scale. The cut-off value for each antigen is shown by the dotted line and was based on the mean plus 3SD of the control group. Only statistically significant p values between the controls and the TB patients are shown and were calculated using the Mann Whitney U test with a Bonferroni adjusted P value = 0.006