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Table 2 Correlations between bacterial growth inhibition and soluble factors

From: Leukocyte presence does not increase microbicidal activity of Platelet-rich Plasma in vitro

Bacteria Time Soluble factors
   CCL3/MIP-1α CCL-5/RANTES CXCL1/GRO-α CXCL-8/IL-8 CXCL-7/NAP2 CXCL-12/SDF-1α IL-6
Escherichia coli 1 h --- --- --- --- --- p < 0.05 ---
2 h --- p < 0.05 p < 0.05 --- --- p < 0.005 ---
4 h --- --- p < 0.01 --- --- --- ---
Staphylococcus aureus 1 h p < 0.01 --- p < 0.0001 --- p < 0.01 --- ---
2 h p < 0.005 p < 0.01 --- p < 0.01 p < 0.000005 p < 0.05 ---
4 h p < 0.005 p < 0.05 --- p < 0.01 p < 0.00001 --- ---
Klebsiella pneumoniae 1 h --- p < 0.000005 p < 0.01 p < 0.01 p < 0.001 p < 0.0001 p < 0.01
2 h p < 0.01 --- --- --- --- --- ---
4 h p < 0.01 p < 0.05 --- p < 0.005 p < 0.000005 p < 0.001 p < 0.005
Pseudomonas aeruginosa 1 h --- --- --- --- --- --- ---
2 h p < 0.000005 p < 0.0005   p < 0.01 p < 0.000005 p < 0.005 p < 0.0001
4 h p < 0.0005 p < 0.0005 p < 0.05 p < 0.005 p < 0.000005 p < 0.001 p < 0.0005
Enterococcus faecalis 1 h --- --- --- --- p < 0.005 --- ---
2 h p < 0.000005 p < 0.00005 p < 0.05 p < 0.001 p < 0.0005 p < 0.00005 p < 0.000005
4 h p < 0.05 --- --- --- --- --- ---
  1. Significant correlations between bacterial growth inhibition at different time points and the concentration of soluble factors released by the PRP preparations after 1 h of activation and described with antimicrobial potential, as determined by Kendall-Tau rank correlation test