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Table 2 Factor H binding protein (fHbp) peptide types in invasive Neisseria meningitidis from Québec, Canada, 2009-2013

From: Characterization of invasive Neisseria meningitidis strains from Québec, Canada, during a period of increased serogroup B disease, 2009-2013: phenotyping and genotyping with special emphasis on the non-carbohydrate protein vaccine targets

Novartis variant 1

Peptides

# of isolates (serogroup)

(Pfizer subfamily B)

1.1

2 (B, two ST-32 cc)

 

1.4

5 (B, four ST-41/44 cc, one ST-35 cc)

 

1.12

2 (B, one UAa; C, one ST-11 cc)

 

1.13

5 (B, one ST-60 cc, one ST-254 cc, two ST-1157 cc, one UA)

 

1.14

1 (B, ST-41/44 cc)

 

1.15

152 (B, 152 ST-269 cc)

 

1.100

1 (B, ST-41/44 cc)

 

1.110

1 (B, UA)

 

1.129

1 (C, ST-11 cc)

 

1.144

1 (B, ST-32 cc)

 

1.218

1 (C, ST-11 cc)

 

1.249

1 (B, ST-269 cc)

 

1.278

1 (Y, ST-167 cc)

 

1.410

4 (B, four ST-41/44 cc)

 

1.687

1 (B, ST-41/44 cc)

Novartis variant 2

2.16

15 (3B, three ST-35 cc; 1C, ST-11 cc; 2Y, one ST-22 cc; one UA; 9W, nine ST-22 cc)

(Pfizer subfamily A)

  
 

2.19

32 (31B, five ST-269 cc; 26 ST-41/44 cc; 1×, one ST-32 cc)

 

2.21

1 (Y, ST-174 cc)

 

2.22

1 (B, ST-32 cc)

 

2.23

6 (3B, two ST-41/44 CC; one ST-37 cc; 3Y, one ST-167 cc; two UA)

 

2.24

5 (4B, two ST-41/44 cc, two UA; 1Y, ST-167 cc)

 

2.25

9 (1B, ST-103 cc; 7Y, six ST-23 cc; one ST-167 cc; 1 W, ST-22 cc)

 

2.102

2 (1B, ST-213 cc; 1C, ST-11 cc)

 

2.106

1 (B, UA)

 

2.527

1 (B, UA)

 

2.629

1 (Y, UA)

 

2.632

1 (B, ST-41/44 cc)

Novartis variant 3

3.30

2 (B, ST-41/44 cc, ST-32 cc)

(Pfizer subfamily A)

3.47

2 (B, two ST-461 cc)

 

3.555

1 (B, UA)

No peptide

allele 669

2 (C, two ST-11 cc)

 

allele 755

1 (B, ST-269 cc)

Recombination

disrupted gene

1 (B, UA)

  1. aUA = not assigned to any known clonal complex by pubmlst.org/neisseria