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Table 2 The strongest rules for highly and low pathogenic viruses from the HA classifier

From: A complete map of potential pathogenicity markers of avian influenza virus subtype H5 predicted from 11 expressed proteins

 

Rule

Accuracy (%)

Support

Class-Specific-Coverage (%)

HP-Rules

IF P43(HA1) = D THEN virus = HP

99.8

1225

86

IF P83(HA1) = A THEN virus = HP

100.0

807

57

IF P71(HA1) = I THEN virus = HP

100.0

759

53

LP-Rules

IF P43(HA1) = S THEN virus = LP

95.2

589

99

IF P83(HA1) = D THEN virus = LP

94.6

571

95

IF P107(HA1) = S THEN virus = LP

95.8

552

93

IF P138(HA1) = N THEN virus = LP

92.7

536

88

IF P309(HA1) = D THEN virus = LP

94.9

533

89

IF P320(HA1) = V THEN virus = LP

95.7

532

90

IF P195(HA1) = N THEN virus = LP

88.8

400

63

IF P16(SP) = G THEN virus = LP

89.3

392

62

IF P203(HA2) = I THEN virus = LP

82.4

380

55

IF P6(SP) = I THEN virus = LP

97.5

354

61

IF P7(SP) = A THEN virus = LP

98.0

352

61

IF P3(SP) = R THEN virus = LP

94.1

341

57

IF P240(HA1) = S THEN virus = LP

95.2

332

56

IF P275(HA1) = D THEN virus = LP

97.3

300

52

  1. Accuracy is the percentage of the sequences in the support set correctly classified by the rule. Support is the number of sequences that satisfy the “IF” conditions of the rule. Class-Specific-Coverage is the percentage per class (i.e. HP or LP, respectively) of the sequences that support the rule and are correctly classified by the rule. For instance, if a rule is an HP class rule then the Class-Specific-Coverage gives the percentage of the HP sequences classified correctly by this rule