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Table 2 CPS content (μg/ml) following treatment of K. pneumoniae biofilm of different days with phage/bacterial depolymerase (20 units/ml each)

From: Aeromonas punctata derived depolymerase improves susceptibility of Klebsiella pneumoniae biofilm to gentamicin

Biofilm age

CPS content (μg/ml)

Days

Untreated

Phage enzyme treated*

Bacterial enzyme treated#

1

0.989 ± 0.15

0.639 ± 0.22

0.279 ± 0.18

3

1.082 ± 0.24

0.846 ± 0.36

0.357 ± 0.17

5

1.589 ± 0.09

0.978 ± 0.24

0.511 ± 0.15

7

2.014 ± 0.35

1.168 ± 0.28

0.656 ± 0.19

  1. Data is presented as mean ± SD (n = 3). [*p > 0.05 (average CPS content in phage depolymerase treated vs untreated biofilm), # p < 0.05 (average CPS content in bacterial depolymerase treated vs untreated biofilm)]. Denatured bacterial/phage depolymerase heated at 75 °C for 10 min were used as controls for biofilm treatment. But no effect on CPS content was observed