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Table 1 In vitro antibiotic susceptibility of planktonic and biofilm S. pseudintermedius strain DSM 25713 cells. MIC, Minimum Inhibitory Concentration; MBC, Minimum Bactericidal Concentration; MBEC50 and MBEC90, Minimum Concentrations Eradicating respectively 50 % and 90 % of Biofilm viability, compared to untreated controls (100 % viability). Assays were performed in triplicate and repeated on two different occasions (n = 6). Values are mg/L

From: New insights in Staphylococcus pseudintermedius pathogenicity: antibiotic-resistant biofilm formation by a human wound-associated strain

Antibiotics Planktonic cells Biofilm cells C max a
MIC MBC MBEC50 MBEC90
Chloramphenicol 32 256 128 4,096 16.9 [49]
Gentamicin 0.5 0.5 32 32 5-12 [50]
Cefoxitin 16 32 16 1,024 20 [51]
Linezolid 4 32 4 1,024 21.2 [52]
Rifampicin 0.03 0.5 0.03 0.06 10 [53]
Tigecycline 0.5 8 0.5 64 0.25-2.8 [54]
Tetracycline 0.5 8 0.5 64 2 [55]
Vancomycin 2 2 16 32 25 [56]
  1. aMaximum concentration of drug in serum; references are shown in parentheses