Figure 2

Comparison of inflammation measures in severe and moderate colitis models [ 25 ] with the micro-inflammation model employed in this study. Severity of the colitis was assessed from differences in body weight (A), macroscopic score (B), histological score (C) and MPO activity (D) between the control non-inflamed (EtOH-PBS), control inflamed severe colitis model (DNBS-PBS (S-I)) [25], moderate colitis model (DNBS-PBS (M-I)) [25] and micro-inflammation model (DNBS-PBS (Mi-I)). Experiments were performed at least in duplicate. Comparisons involved the non-parametric Kruskal-Wallis test was used followed by a Dunn’s Multiple Comparison test. *p < 0.05 vs. DNBS-PBS, +p < 0.05 (n = 16 mice per group).