Table 1 Productivity related parameters of Pichia pastoris GAPMP1102 for fed-batch fermentation under different pH conditions

Total protein (mg/l)

807.42 ± 26.35

913.28 ± 22.94

1076.99 ± 35.86

1213.64 ± 42.68

1127.38 ± 37.62

rMP1102 (mg/l)

367.59 ± 13.51

423.62 ± 18.27

486.35 ± 17.96

538.17 ± 21.32

503.92 ± 19.85

Activity (AU/ml × 10000)

3.84 ± 0.31

5.12 ± 0.28

10.24 ± 0.36

15.36 ± 0.43

10.24 ± 0.37

Max cell wet weight (g/l)

341.2 ± 19.41

378.5 ± 17.13

410.7 ± 16.29

424.9 ± 25.81

402.6 ± 21.74

Specific cell growth rate (μ)

0.188

0.189

0.208

0.224

0.198

Productivity (AU/mg rMP1102)

104464

120863

210548

285412

203207