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Figure 2 | BMC Microbiology

Figure 2

From: Genome-wide identification of Bacillus subtilis Zur-binding sites associated with a Zur box expands its known regulatory network

Figure 2

Zur box motifs present in Zur-binding sites identified in ChIP-on-chip experiments. (A) The 20 nt palindromic consensus sequences identified from the in vivo Zur binding sites. The size of the nucleotide at each position indicates its relative prevalence in sequences used as training set for MEME algorithm [30]. (B) Alignment of the motif identified in this work with the previously reported Zur box, Fur box and PerR box. Common nucleotides are indicated in bold. (C) Alignment of Zur box sequences: (i) Zur boxes in promoter regions of genes belonging to the Zur regulon; (ii) intragenic Zur boxes in Zur binding regions detected by ChIP-on-chip. Nucleotides matching the consensus (plain) and nucleotides different from the consensus (bold) are indicated. Stars mark the critical positions for Zur binding as previously described [11].

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