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Figure 2 | BMC Microbiology

Figure 2

From: Extragenic suppressor mutations in ΔripA disrupt stability and function of LpxA

Figure 2

The biosynthetic pathway of LpxA and GlmU. UDP-N-acetylglucosamine (UDP-GlcNAc) is synthesized from fructose-6-phosphate with the last two sequential steps synthesized by the bifunctional acetyltransferase and uridyltransferase, GlmU. The substrate UDP-glucosamine is either used by LpxA in conjunction with acyl-ACP in a reversible reaction to make a precursor molecule of lipid A, or is used by MurA to make a precursor molecule of the cell wall.

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