Figure 2
From: Plasminogen activation by staphylokinase enhances local spreading of S. aureus in skin infections
Adenoviral-mediated human plasminogen expression. Human plasminogen (huPlg) expression in murine plasma after administration of 5 × 1010 viral particles of adenoviral vector Adplasm. Day 0 is the day of subcutaneous infection with S. aureus Xen36, 7 to 11 days after adenoviral injection. Values from Adnull injected mice are included as negative controls. The expression of huPlg during the whole course of the subcutaneous infection experiment allows the selective interaction of staphylokinase with huPlg.