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Figure 7 | BMC Microbiology

Figure 7

From: Activation of gab cluster transcription in Bacillus thuringiensis by γ-aminobutyric acid or succinic semialdehyde is mediated by the Sigma 54-dependent transcriptional activator GabR

Figure 7

Schematic diagram of the regulatory pattern of the gab gene cluster in Bt. The hollow arrows (from left to right) indicate the gabT, gabR, and gabD genes. PgabT and PgabR are the putative promoter regions of gabT and gabR, respectively. The dashed circle indicates the TCA cycle. There are two transcriptional units, gabT and gabRD, in the gab gene cluster involved in the GABA shunt. GABA and SSA are the signals that induce gabT transcription via the PAS domain of GabR. Transcription of gabT is controlled by Sigma 54, and activated by GabR, via the binding to the 96-bp fragment of the gabT promoter.

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