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Table 2 MIC of amphotericin B against C. albicans SC5314, LBF and HBF

From: Extracellular DNA release confers heterogeneity in Candida albicans biofilm formation

Minimum inhibitory concentrations (MICs)
Strain 4 h biofilm 24 h biofilm
  AMB MIC50 *(mg/L) FC** + DNase FC + AZE AMB MIC50(mg/L) FC + DNase FC + AZE
SC5314 <0.0313 1 1 0.5 4 2
LBF 0.0313 1 1 0.25 – 0.5 1 - 2 1
HBF 0.125 – 0.25 1 - 2 1 0.25 - 1 4 - 8 2
  1. *MIC50 – Minimum concentration of AMB at which 50% reduction in viability assessed by XTT assay.
  2. **FC – Fold change in MIC of AMB in the presence and absence of DNase or acetazolamide (AZE).