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Table 2 Comparison between M. tuberculosis and M. smegmatis for nutrient utilization

From: Identifying feasible metabolic routes in Mycobacterium smegmatis and possible alterations under diverse nutrient conditions

Carbon source

Mtb

Msm

Carbon source

Mtb

Msm

2-oxoglutarate

✓

NA

Oxalomalate

✓

NA

Acetate

✓

✓

Propanoate

X

✓

Acetoacetic acid

✓

NA

Pyruvate

✓

✓

Adenosine

X

X

D-serine

✓

X

D-alanine

✓

✓

D-tagatose

X

NA

L-alanine

✓

✓

D-trehalose

✓

✓

L-asparagine

✓

✓

Tween 20

✓

✓

Butyrate

✓

✓

Tween 40

✓

✓

Caproic acid

✓

✓

Tween 80

✓

✓

Citrate

✓

✓

   

D-fructose-6-phosphate

✓

✓

Nitrogen source

  

D-glucose-6-phosphate

✓

✓

L-Alanine

✓

✓

D-glucose

✓

✓

Allantoin

X

✓

L-glutamate

✓

✓

L-Asparagine

✓

✓

L-glutamine

✓

✓

L-Aspartic acid

X

✓

Glycerol

✓

✓

L-Cysteine

✓

✓

Glycine

✓

NA

D-Galactosamine

✓

✓

L-lactate

✓

✓

D-Glucosamine

X

✓

D-malate

X

✓

L-Glutamic acid

✓

✓

L-malate

✓

✓

L-Glutamine

✓

✓

D-mannose

X

✓

L-Ornithine

✓

✓

Methyl-pyruvate

✓

✓

D-Serine

✓

✓

Mono methyl-succinate

✓

✓

L-Serine

✓

✓

N-acetyl-glucosamine

X

✓

L-Threonine

X

✓

  1. The nutrient sources in bold indicate the differential utilization by Msm and Mtb. (?=growth, X=no growth, NA=not available).