Table 3 Structure of most effective inhibitors of SrtB ΔN26
From: Clostridium difficilehas a single sortase, SrtB, that can be inhibited by small-molecule inhibitors
Compound | Structure | IC50 |
|---|---|---|
LSHTM-0040 |  | 63.1 ± 8.8 μM |
LSHTM-0050 |  | 60.1 ± 4.7 μM |
LSHTM-0052 |  | 44.1 ± 6.9 μM |