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Table 3 List of encoded oxygenase enzymes from the hpi , amb and wel biosynthetic gene clusters

From: Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria

Enzyme FS ATCC 43239 FS PCC 9339 FA UTEX 1903 HW IC-52-3 WI HT-29-1 FS PCC 9431 FM SAG 1427-1 % identity
Oxygenases         
Rieske oxygenase - - AmbO1 - - - - -
Rieske oxygenase - - AmbO2 - - - - -
Rieske oxygenase - - AmbO3 - - - - -
Rieske oxygenase - HpiO4 AmbO4 - - - - 100
Oxidoreductase, 2OG-Fe(II) oxygenase family - HpiO5 AmbO5 - - - - 98.1
Alkanesulfonate monooxygenase - HpiO6 AmbO6 - - - - 100
Oxidoreductase, FAD dependent pyridine nucleotide disulfide - - AmbO7 - - - - -
Rieske oxygenase HpiO8 HpiO8 - - - - - 100
Rieske oxygenase HpiO9 - - - - - - -
Oxidoreductase, FAD dependent HpiO10 - - - - - - -
Rieske oxygenase - - - WelO11 WelO11 - - 90.9
Rieske oxygenase - - - WelO12 WelO12 WelO12 - 99.1
Rieske oxygenase - - - WelO13 WelO13 -   97.8
Rieske oxygenase - - - WelO14 WelO14 WelO14 - 98.1
Oxidoreductase, 2OG-Fe(II) oxygenase family - - - WelO15 WelO15 WelO15 - 96.3
Indoleamine 2,3-dioxygenase - - - WelO16 WelO16 WelO16 - 99.0
Choline dehydrogenase-like flavoprotein - - - WelO17 WelO17 WelO17 - 99.0
Monooxygenase - - - - WelO18 - WelO18 99.0
Rieske oxygenase - - - - WelO19 - WelO19 98.3