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Table 2 Effect of phage on adhesion, invasion and cytotoxicity of NEC by additional clinical strains of S. aureus (MRSA)

From: Bacteriophage as effective decolonising agent for elimination of MRSA from anterior nares of BALB/c mice

Strains (Bacteria: NEC- 10:1) Mean percent (%)
Adherence Invasion Cytotoxicity (24 h)
No phage Phage (MOI-1) Phage (MOI-10) No phage Phage (MOI-1) Phage (MOI-10) No phage Phage (MOI-1) Phage (MOI-10)
S. aureus ATCC 43300 (MRSA) 73.7 0.41 0.025 31.9 0.031 No invasion 11.1 0.21 No cytotoxicity
S. aureus ATCC 29213 (MSSA) 76.8 0.51 0.034 18.4 0.034 No invasion 10.2 0.23 No cytotoxicity
S. aureus CS-1 68.4 0.37 0.066 28.1 0.06 No invasion 11.4 0.41 No cytotoxicity
S. aureus CS-2 62.5 0.32 0.074 25.4 0.064 No invasion 10.1 0.43 No cytotoxicity
S. aureus CS-3 74.8 0.45 0.084 33.3 0.078 No invasion 14.5 0.64 No cytotoxicity
S. aureus CS-4 70.4 0.34 0.081 30.4 0.072 No invasion 14 0.61 No cytotoxicity
S. aureus CS-5 72.1 0.33 0.075 32.8 0.066 No invasion 13.3 0.72 No cytotoxicity
  1. (CS-1 to CS-5 : these are clinical strains (CS) of MRSA chosen at random to test for their adherence, invasion and cytotoxicity parameters on cultured murine NEC).