Figure 5

Histopathological analysis showing. A) Photo micrograph of skin tissue of nasal mucosa of untreated colonised mice on day 2 post colonisation showing mild inflammation with recruitment of few acute inflammatory cells(red arrows) (H and E 100X). B) and C) Photo micrograph of skin tissue of nasal mucosa of untreated colonised mice on day 5 post colonisation showing marked sub epithelial inflammation rich in neutrophils and plasma cells (H and E 100X and 200X). D) and E) Photo micrograph of skin tissue of nasal mucosa of phage treated (group 3) and Mupirocin treated(group 4) mice on day 5 post treatment showing mild infiltration in the sub epithelial lining (H and E 100X). F) Photo micrograph of skin tissue of nasal mucosa of mice receiving combined therapy (group 5) with nearly normal skin (H and E 100X).