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Table 2 Single nucleotide polymorphisms (SNPs) upon change of phenotype from 307.14 encapsulated to 307.14 nonencapsulated

From: A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence

Gene product (TIGR4, GenBank AE005672.3)

SNP position in gene (307.14)

Base change amino acid change

Undecaprenylphosphate glucosephosphotransferase (CpsE) (SP_0350)

1135

C → G

Arg → Gly

61 bp upstream ABC transporter, ATP-binding protein (SP_1282)

not applicable

A → G

not applicable

NOL1/NOP2/sun family protein (SP_1402)

553

G → A

Asp → Asn

Transposase, IS3 family, degenerate (SP_2018)

not applicable

T → G

not applicable

dlt B protein (SP_2175)

449

A → G

Stop → Trp

D-alanine-activating enzyme (SP_2176)

514

A → G

Asn → Asp

Translation elongation factor Ts (SP_2214)

919

G → A

Glu → Lys