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Table 1 List of 60 genes that are expressed 3-fold and higher in the wild-type versus Δ bsaN mutant strains (p < 0.01)

From: Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon

Gene locus ID Gene Protein description Fold activation
T3SS3 associated  
BPSS1512 tssM ubiquitin-specific proteinase 9.3
BPSS1513    7.5
BPSS1514 folE GTP hydrolase 5.1
BPSS1515    9.0
BPSS1516 bopC T3SS-3 effector 48.2
BPSS1518   transposase 44.3
BPSS1519   transposase 10.1
BPSS1523 bicP T3SS-3 chaperone 149.0
BPSS1524 bopA T3SS-3 effector 269.4
BPSS1525 bopE T3SS-3 effector 51.7
BPSS1526 bapC T3SS-3 effector 5.9
BPSS1527 bapB T3SS-3 effector 6.8
BPSS1528 bapA T3SS-3 effector 7.6
BPSS1529 bipD T3SS-3 translocon 7.6
BPSS1531 bipC T3SS-3 translocon 6.3
BPSS1532 bipB T3SS-3 translocon 6.6
BPSS1533 bicA T3SS-3 chaperone 9.4
T6SS1 apparatus  
BPSS1497 tssB T6SS-1 3.1
BPSS1498 hcp T6SS-1 11.3
Actin based motility
BPSS1490   N-acetylmuramoyl-L-Ala-amidase 13.5
BPSS1491   ADP-heptose:LPS transferase 8.8
BPSS1492 bimA Bim actin polymerization protein 7.8
BPSS1493    14.5
Polyketide biosynthesis
BPSL0472-BPSL0493   NRPKS/PKS biosynthesis locus 3.0-4.3
BPSL2883   Glyoxalase/bleomycin resistance protein/dioxygenase 4.0
Amino acid biosynthesis and sugar uptake  
BPSL0196 metW methionine biosynthesis protein MetW 4.2
BPSL0197 metX homoserine O-acetyltransferase 3.4
BPSS1691 metZ O-succinylhomoserine sulfhydrylase 3.2
BPSS0005 kbl 2-amino-3-ketobutyrate CoA ligase 6.3
BPSS0006 tdh L-threonine dehydrogenase 5.5
BPSL1793   Periplasmic binding protein (ribose binding) 3.4
Regulatory  
BPSS1494 virG T6SS-1 response regulator 22.4
BPSS1495 virA T6SS-1 His kinase 15.8
BPSS1520 bprC T3SS-3 AraC-type regulator 24.5
BPSS1521 bprD T3SS-3 regulator 151.5
BPSS1522 bprB T3SS-3 response regulator 89.5
BPSS1530 bprA T3SS-3 HNS-type regulator 6.9
BPSL0480 syrP NPKS/PKS regulator 3.9