| |
Compound
|
Fluconazole
| | |
|---|
|
Compounds
|
MIC (μg/mL)
|
MIC combined (μg/mL)
|
FIC*
|
MIC (μg/mL)
|
MIC combined (μg/mL)
|
FICa
|
FICIb
|
Outcome
|
|---|
|
1
|
68.4
|
4.3
|
0.063
|
256
|
4
|
0.016
|
0.079
|
Synergy
|
|
2
|
70.0
|
4.4
|
0.063
|
256
|
4
|
0.016
|
0.079
|
Synergy
|
|
3
|
74.4
|
2.3
|
0.030
|
256
|
4
|
0.016
|
0.046
|
Synergy
|
|
5
|
74.9
|
2.3
|
0.031
|
256
|
4
|
0.016
|
0.047
|
Synergy
|
- *This assay was done with organotellurides and fluconazole isolated or combined.
- MICs were determined by a microdilution technique based on 80% reduction of growth. aFIC = fractional inhibitory concentration; bFICI = fractional inhibitory concentration index.
