Skip to main content

Table 3 Glucose-dependent genes regulated by CcpA and additional factors1

From: Effect of a glucose impulse on the CcpA regulon in Staphylococcus aureus

ID   Producta wt mut
N315 Newman common   +/-b +/-b
SA0432 NWMN_0438 treP PTS system, trehalose-specific IIBC component 0.5 0.2
SA0433 NWNM_0439 treC alpha-phosphotrehalose 0.7 0.3
SA0434 NWNM_0440 treR trehalose operon repressor 0.7 0.3
SA1218 NWNM_1297 pstB phosphate ABC transporter, ATP-binding protein (PstB) 0.5 2.6
SA1219 NWNM_1298   similar to phosphate ABC transporter 0.4 2.7
SA1220 NWNM_1299   similar to phosphate ABC transporter 0.3 3.7
SA1221 NWNM_1300 pstS thioredoxine reductase 0.1 3.6
SA1586 NWNM_1659 ribH 6,7-dimethyl-8-ribityllumazine synthase 0.6 2.2
SA1587 NWNM_1660 ribA riboflavin biosynthesis protein 0.6 1.8
SA1588 NWNM_1661 ribB riboflavin synthase alpha chain 0.7 2.0
SA1589 NWNM_1662 ribD riboflavin specific deaminase 0.7 2.0
SA1960 NWNM_2057 mtlF PTS system, mannitol specific IIBC component 6.4 0.2
SA1961 NWNM_2058   similar to transcription antiterminator BglG family 0.9 0.4
SA2007 NWNM_2110 alsD alpha-acetolactate decarboxylase 9.1 2.7
SA2008 NWNM_2111 alsS alpha-acetolactate synthase 9.1 3.1
SA2293 NWNM_2401 gntP gluconate permease 0.7 2.5
SA2294 NWNM_2402 gntK gluconate kinase 1.6 3.7
*SA2295 NWNM_2403 gntR gluconate operon transcriptional repressor 1.5 3.2
SA2321 NWMN_2432   hypothetical protein 0.1 2.5
SA2434 NWNM_2540   PTS system, fructose-specific IIABC component 1.2 0.4
SA2435 NWNM_2541 pmi mannose-6-phosphate isomerase 1.2 0.4
  1. 1Genes with parallel glucose-mediated regulation in wild-type and mutant but with different ratios, genes with divergent glucose-mediated regulation in wild-type and mutant, and genes with glucose-mediated regulation in the mutant but not in the wild-type
  2. a Cellular main roles are in accordance with the N315 annotation of the DOGAN website [26]and/or the KEGG website [27].
  3. b Comparison of gene expression with (+) and without (-) glucose, genes with a +/- ratio of ≤ 0.5 or ≥2 in the wild-type and the mutant were considered to be regulated)
  4. * Genes containing putative cre-sites