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Table 1 Inhibition summary of Emodin against HpFabZ and H. pylori strains

From: Emodin targets the β-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization

HpFabZ enzyme inhibition

 

IC50 (μM)

9.7 ± 1.0

Inhibition type

Competitive

Ki (μM)

1.9 ± 0.3

H. pylori stain inhibition (MIC in μg/ml)

 

H. pylori SS1

5

H. pylori ATCC

10

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BMC Microbiology

ISSN: 1471-2180

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