Figure 7From: Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesisDhMotC interferes with vacuolar acidification in yeast. Quinacrine staining of yeast under different conditions: Cells were incubated with DMSO, 60 μM dhMotC or 50 μM concanamycin A, stained with the lysosomotropic dye quinacrine and visualized by fluorescence microscopy. Right panel shows control cells in phase contrast microscopy (PC).Back to article page