Figure 3
From: Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair
Assessment of meningococcal (Mc) phase variation. Phase variation frequency for Mc strains NmZ1099_UROS (Control), NmZ1099_UROSΔfpg (Δfpg) and NmZ1099_UROSΔmutS (ΔmutS) as examined by a spectinomycin assay. The results are given as the median of at least 5 independent measurements. Error bars represent ± 1 quartile. Phase variation is moderately and significantly increased, respectively, in the Mc Δfpg (2-fold) and ΔmutS (30-fold) background compared to the wild-type level (***p < 0.001).