L. plantarum inhibits increases in macromolecular permeability of Caco-2 cells in response to EIEC infection. Macromolecular permeability assays with Caco-2 cell monolayers using an infrared sensitive dextran (10-kDa) probe. (◇)represented control group, (■) EIEC group, (▲) L. plantarum group. Dextran integrated intensity after EIEC infected was significantly increased than the control group after cultured 60 min during 120 min. One-way ANOVA was performed with Tukey Kramer post-hoc comparison. * vs control group, P < 0.05; ** vs L. plantarum group, P < 0.05.