Figure 4

Decrease in mouse survival in four passages during adaptation by serial passage (experiment 2). Panel A, C. jejuni 11168; panel B, C. jejuni D0835; panel C, C. jejuni D2600; panel D, C. jejuni D2586. No control mice or mice infected with strain NW required early euthanasia (data not shown). All mice in all passages experienced a dietary shift from an ~12% fat diet to an ~6% fat diet 3 to 5 days prior to inoculation with C. jejuni. Passages 1, 2, and 3 had five infected mice each for each strain; passage four had 10 infected mice. Passage 1 had four sham inoculated control mice; passages 2 and 3 had five control mice each; passage four had 10 control mice.