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Table 4 Frequency of 57 shared spoligotypes (SITs) according to Brudey et al. [21], identified in 188 M. tuberculosis strains isolated with S315T mutation, from South America.

From: Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosisclinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America

Lineage

SIT

Number of isolates

Number of DRE-PCR patterns

Number of isolates in cluster (%)

Beijing

1

3

2

2 (66.7)

Haarlem1

47

6

6

0

Haarlem3

50

19

16

6 (31.5)

Haarlem3

49

3

2

2 (66.7)

LAM1

20

9

4

7 (77.8)

LAM2

17

6

3

3 (50.0)

LAM3

33

8

4

4 (50.0)

LAM3/S convergent

4

3

2

2 (66.7)

LAM3

211

2

1

2 (100)

LAM4

828

3

3

0

LAM5

93

10

6

4 (40.0)

LAM6

64

9

6

2 (22.2)

LAM9

435

3

1

3 (100)

LAM9

177

3

3

0

LAM9

388

2

1

2 (100)

LAM9

42

22

12

14 (63.6)

S

1938

7

5

4 (57.0)

T1

53

17

11

4 (23.5)

U

397

3

2

2 (66.7)

U

402

2

2

0

U

1241

3

3

0

X1

119

3

3

0

X2

137

2

2

0

X3

92

3

2

2 (66.7)

X3

91

3

3

0

LAM4

60

2

2

0

U

602

2

2

0

T5-MAD2

58

1

Not done

Unique

LAM6

95

1

Not done

Unique

U (LAM3?)

106

1

Not done

Unique

T5

68

1

Not done

Unique

T3

157

1

Not done

Unique

T1

159

1

Not done

Unique

Haarlem3

207

1

Not done

Unique

T1

253

1

Not done

Unique

Beijing-Like

269

1

Not done

Unique

T1

353

1

Not done

Unique

T1

453

1

Not done

Unique

Haarlem3

631

1

Not done

Unique

S

707

1

Not done

Unique

S

827

1

Not done

Unique

LAM5-LAM6

867

1

Not done

Unique

X2

1341

1

Not done

Unique

T2

1355

1

Not done

Unique

LAM9

1535

1

Not done

Unique

LAM2

1691

1

Not done

Unique

LAM1

389

1

Not done

Unique

T1

276

1

Not done

Unique

Haarlem3

294

1

Not done

Unique

MANU2

1094

1

Not done

Unique

LAM5

176

1

Not done

Unique

T3

1655

1

Not done

Unique

LAM3

130

1

Not done

Unique

T4-CE1 ancestor?

65

1

Not done

Unique

Haarlem3-LAM9

335

1

Not done

Unique

T1

222

1

Not done

Unique

LAM3

1354

1

Not done

Unique