Figure 1
From: NF-κB activation by Helicobacter pylorirequires Akt-mediated phosphorylation of p65
Phosphorylation of Akt in H. pylori -infected gastric mucosa. Immunohistochemical detection of phosphorylated Akt in tissues of patients with H. pylori-positive gastritis. Serial sections of gastric biopsy specimens were stained with monoclonal antibody against phospho-Akt (serine 473). (A and B) Representative examples of mucosa from patients with H. pylori-positive gastritis. (C and D) Representative examples of normal mucosa. Note the positive staining for phospho-Akt in the mucosal epithelial cells of patients with H. pylori-positive gastritis. Original magnification, ×200.