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Table 3 Classes of biological processes involving up regulatedpig gene homologues (p-value < 0.01) in brain and lung tissues infected with wild type PRV.

From: Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus

Biological Process

Library

Brain Pig Unigene Matches over 60 base-pairs (gene homologues)

Brain Pig

Ungene

Matches

between 50-

59b base-pairs (gene

homologues)

Lung Pig Unigene Matches over 60 base-pairs (gene homologues)

Lung Pig Unigene Matches between 50-59b base-pairs (gene homologues)

Apoptosis

230

3*

0

30*

4

Biological function unknown

472

4

0

31

10

Cation transport

139

2*

3*

0

2

Cell adhesion

429

8*

5*

11

4

Cell cycle

303

3

0

31*

3

Cell differentiation

230

4*

1*

7

2

Immune response

255

0

0

7

3

Intracellular protein transport

135

5*

0

16*

5*

Intracellular signaling cascade

285

4*

0

14

3

Ion transport

304

5*

1

6

4

Metabolism

280

3*

3

15*

9*

Nervous system development

239

9*

3*

9

3

Protein amino acid dephosphorylation

108

1

2*

14*

1

Protein amino acid phosphorylation

412

1

2*

29

7

Protein folding

165

4*

0

27*

5*

Protein transport

217

2

2*

33*

4

Proton transport

47

1*

2*

3

7*

Regulation of progression through cell cycle

215

2

2*

20*

4

Regulation of transcription, DNA dependent

1285

9

2

73

7

Signal transduction

1110

6

1

40

6

Synaptic transmission

164

4*

4*

5

1

Transcription

945

7

1

63

7

Ubiquitin cycle

217

1

0

30*

4

  1. * Biological processes with at least two times the expected number of genes (calculated from the library composition).