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Table 3 Survival rates, presence of exotoxin A, culture results and colony counts in the experimental group (immunized mice) inoculated with P. aeruginosa

From: Active immunization using exotoxin A confers protection against Pseudomonas aeruginosainfection in a mouse burn model

Post-inoculation

time (day)

Number of

animals alive

(survival rate, %)

CFU/mL from

inoculated

burns

Exotoxin A

in sera

(%)*

Positive

culture

(%)

Number of

animals alive

(survival rate, %)

     

Liver

Spleen

Blood

1

48 (100)

1.5 × 108

ND

48 (100)

-

-

-

4

48 (100)

1.4 × 107

ND

48 (100)

-

-

-

7

47 (98)

1.3 × 106

ND

47 (100)

1 (2)

1 (2)

1 (2)

11

46 (96)

1.2 × 105

ND

47 (98)

1 (2)

1 (2)

1 (2)

14

45 (94)

1 × 104

ND

45 (94)

1 (2)

1 (2)

1 (2)

  1. ND, not detectable by CIEP; * neutralizing antibody detected