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Table 3 Survival rates, presence of exotoxin A, culture results and colony counts in the experimental group (immunized mice) inoculated with P. aeruginosa

From: Active immunization using exotoxin A confers protection against Pseudomonas aeruginosainfection in a mouse burn model

Post-inoculation
time (day)
Number of
animals alive
(survival rate, %)
CFU/mL from
inoculated
burns
Exotoxin A
in sera
(%)*
Positive
culture
(%)
Number of
animals alive
(survival rate, %)
      Liver Spleen Blood
1 48 (100) 1.5 × 108 ND 48 (100) - - -
4 48 (100) 1.4 × 107 ND 48 (100) - - -
7 47 (98) 1.3 × 106 ND 47 (100) 1 (2) 1 (2) 1 (2)
11 46 (96) 1.2 × 105 ND 47 (98) 1 (2) 1 (2) 1 (2)
14 45 (94) 1 × 104 ND 45 (94) 1 (2) 1 (2) 1 (2)
  1. ND, not detectable by CIEP; * neutralizing antibody detected