Table 1 Summary of transcriptional changes in B. cereus ATCC14579 upon 0.5 μg/ml AS-48 treatment
Locus tag | Expression ratioa | Significance (p-value)b | Annotationc | Featured |
|---|---|---|---|---|
Upregulated | ||||
BC4206 | 8.7 | < 10-14 | PadR-like transcriptional regulator | PR |
BC4207 | 8.7 | < 10 -14 | Hypothetical protein | TMS(4) |
BC4027 | 4.7 | < 10 -14 | NADH dehydrogenase subunit N | TMS(6) |
BC2842 | 4.0 | 10 -12 | Hypothetical protein | SS; TMS(2) |
BC5438 | 3.7 | 10 -12 | Antiholin-like protein | TMS(7) |
BC1612 | 3.7 | 10 -13 | Na+/H+ antiporter | SS; TMS (11) |
BC2300 | 3.0 | 10 -11 | Oxalate/formate antiporter | SS; TMS(11) |
BC5439 | 2.7 | 10 -10 | Murein hydrolase regulator | SS; TMS(4) |
BC4528 | 2.4 | 10-11 | Ferrichrome-binding protein | PPD |
BC4028 | 2.4 | 10 -10 | NADH dehydrogenase subunit N | TMS(6) |
BC4268 | 2.4 | 10 -8 | Phosphate transport system permease protein | TMS(6) |
BC4269 | 2.3 | 10-9 | Phosphate-binding protein | SS |
BC4362 | 2.2 | 10 -7 | Ferrichrome transport system permease protein | TMS(9) |
BC0223 | 2.2 | 10 -9 | Hypothetical protein | SS; TMS(1) |
BC4029 | 2.2 | 10-11 | PadR-like transcriptional regulator | PR |
BC5100 | 2.1 | 10 -8 | Hypothetical protein | SS; TMS(1) |
BC0383 | 2.1 | 10-10 | Ferrichrome-binding protein | SS, PPD |
BC3540 | 2.1 | 10-9 | BNR-repeat containing protein | |
BC3541 | 2.1 | 10-7 | Flavodoxin | Flavodoxin |
BC0227 | 2.0 | 10 -9 | Hypothetical protein | TMS(1) |
Downregulated | ||||
BC0409 | 0.3 | 10-12 | Carbamate kinase | Kinase |
BC0406 | 0.3 | 10-12 | Arginine deiminase | Aminidotransferase |
BC0407 | 0.3 | 10-12 | Ornithine carbamoyltransferase | Carbamoyl-P binding domain; Asp/Orn binding domain |
BC0408 | 0.3 | 10 -12 | Arginine/ornithine antiporter | Permease; TMS(1) |